Hydrogen bonding in DNA base complexes
نویسندگان
چکیده
منابع مشابه
Hydrogen bonding, base stacking, and steric effects in dna replication.
Understanding the mechanisms by which genetic information is replicated is important both to basic knowledge of biological organisms and to many useful applications in biomedical research and biotechnology. One of the main functions of a DNA polymerase enzyme is to help DNA recognize itself with high specificity when a strand is being copied. Recent studies have shed new light on the question o...
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molecules to evolve in the test tube. With the discovery of catalytic RNA, and advances in nucleic acid amplification techniques such as the polymerase chain reaction, it became possible to construct laboratory systems that allow the Darwinian evolution of functional RNA (and later DNA) molecules. This is not evolution based on natural selection, but rather directed evolution based on selection...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1981
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(81)84851-5